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Green Tea
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Effect of green tea on N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in rats Journal of the Medical Society of Toho University (Japan) , 1996, 42/6 (642-645)
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Green Tea
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Effect of green tea on N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in rats Journal of the Medical Society of Toho University (Japan) , 1996, 42/6 (642-645)
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The effect of green tea on N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)-induced urinary bladder carcinogenesis in rats was investigated. Fifty male WISTAR rats, seven weeks of age, were divided into two groups and BBN was added to their drinking water with a concentration of 0.05% for 5 weeks. The drinking water was then replaced with tap water for the control group and green tea for the green tea group. All rats were sacrificed at 40 weeks. Regarding the mean volume per tumor, there was significant difference between both groups. However, there was no significant difference between both groups in the number of rats with carcinomas and the number of tumors per rat. The body weightgroups and no side effects were noted. These results indicate that oral administration of green tea suppresses the growth of urinary bladder tumors in rats induced by BBN.
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